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The usual dose by mouth is one capsule of 250 mg 4 times a day in adults and half the adult dose as a syrup for children under the age of 10 years but over 2. [4] For children below the age of 2 years, the oral dose is a quarter of the adult oral dose. [3] Ampicillin/flucloxacillin is taken orally about half an hour before food. [5]
Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1] It is taken by mouth. [1] It was approved for medical use in the United States in 2006. [1]
[1] [11] Antibiotics should generally not be used. [12] An exception is when acute bronchitis is due to pertussis. [1] Tentative evidence supports honey and pelargonium to help with symptoms. [1] Acute bronchitis is one of the most common diseases. [3] [13] About 5% of adults are affected and about 6% of children have at least one episode a year.
Protracted bacterial bronchitis in children, is defined as a chronic productive cough with a positive bronchoalveolar lavage that resolves with antibiotics. [ 77 ] [ 78 ] Protracted bacterial bronchitis is usually caused by Streptococcus pneumoniae , non-typable Haemophilus influenzae , or Moraxella catarrhalis . [ 78 ]
Some cough medicines may be no more effective than placebos for acute coughs in adults, including coughs related to upper respiratory tract infections. [7] The American College of Chest Physicians emphasizes that cough medicines are not designed to treat whooping cough , a cough that is caused by bacteria and can last for months. [ 8 ]
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. but with an N-oxime side chain attached to the ring. Roxithromycin was patented in 1980 and approved for medical use in 1987. [1]