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A biologics license application (BLA) is defined by the U.S. Food and Drug Administration (FDA) as follows: The biologics license application is a request for permission to introduce, or deliver for introduction, a biologic product into interstate commerce (21 CFR 601.2). The BLA is regulated under 21 CFR 600 – 680.
It can be present as an undeclared ingredient in black market products available online to enhance athletic performance. Like other substances with anabolic properties, clomifene leads to increased muscle mass in males. [25] Because clomifene can enhance egg production in hens, athletes may inadvertently consume the substance through ...
Benzothiophene is an aromatic organic compound with a molecular formula C 8 H 6 S and an odor similar to naphthalene (mothballs). It occurs naturally as a constituent of petroleum-related deposits such as lignite tar.
Serpins are a superfamily of proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. [1] [2] The acronym serpin was originally coined because the first serpins to be identified act on chymotrypsin-like serine proteases (serine protease inhibitors).
Data science also integrates domain knowledge from the underlying application domain (e.g., natural sciences, information technology, and medicine). [3] Data science is multifaceted and can be described as a science, a research paradigm, a research method, a discipline, a workflow, and a profession. [4]
Apple II ("apple two") is a series of microcomputers manufactured by Apple Computer, Inc. from 1977 to 1993. The first Apple II model, that gave the series its name, was designed by Steve Wozniak, and was first sold on June 10, 1977. [2]
The phrase was coined by Marshall McLuhan. "The medium is the message" is a phrase coined by the Canadian communication theorist Marshall McLuhan and the name of the first chapter [1] in his Understanding Media: The Extensions of Man, published in 1964.
On 15 September 2022, the world's second largest cryptocurrency at that time, Ethereum, transitioned its consensus mechanism from proof-of-work (PoW) to proof-of-stake (PoS) in an upgrade process known as "the Merge". According to the Ethereum Founder, the upgrade would cut both Ethereum's energy use and carbon-dioxide emissions by 99.9%.