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  2. Zidovudine - Wikipedia

    en.wikipedia.org/wiki/Zidovudine

    Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. [6] It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. [6]

  3. Lamivudine/zidovudine - Wikipedia

    en.wikipedia.org/wiki/Lamivudine/zidovudine

    Lamivudine/zidovudine, sold under the brand name Combivir among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. [2] It contains two antiretroviral medications, lamivudine and zidovudine. [2] It is used together with other antiretrovirals. [2] It is taken by mouth twice a day. [2] [3]

  4. List of antiretroviral fixed-dose combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_antiretroviral...

    zidovudine: September 26, 1997 ViiV Healthcare: No Kaletra (developed countries) Aluvia (developing countries) lopinavir: ritonavir: September 15, 2000 Abbott Laboratories: No Trizivir: abacavir lamivudine zidovudine November 15, 2000 ViiV Healthcare Yes Epzicom Kivexa (EU, RU) abacavir lamivudine August 2, 2004 ViiV Healthcare No Generics, e.g ...

  5. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. [1] There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy ...

  6. Discovery and development of nucleoside and nucleotide ...

    en.wikipedia.org/wiki/Discovery_and_development...

    The reverse transcriptase of HIV-1 has been the main foundation for the development of anti-HIV drugs. [5] The first nucleoside reverse-transcriptase inhibitor with in vitro anti-HIV activity was zidovudine. [6] Since zidovudine was approved in 1987, six nucleosides and one nucleotide reverse-transcriptase inhibitor (NRTI) have been approved by ...

  7. Reverse-transcriptase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Reverse-transcriptase...

    Zidovudine, also called AZT, ZDV, and azidothymidine, has the trade name Retrovir. Zidovudine was the first antiretroviral drug approved by the FDA for the treatment of HIV. Didanosine, also called ddI, with the trade names Videx and Videx EC, was the second FDA-approved antiretroviral drug. It is an analog of adenosine.

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