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Bruce D. Roth is an American organic and medicinal chemist who trained at Saint Joseph's College, Iowa State University and the University of Rochester, and, at the age of 32, discovered atorvastatin, the statin-class drug sold as Lipitor that would become the largest-selling drug in pharmaceutical history (as of 2003).
Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. [5] For the prevention of cardiovascular disease, statins are a first-line treatment. [5] It is taken by mouth. [5] Common side effects include joint pain, diarrhea, heartburn, nausea, and muscle pains. [5]
Statins are effective and considered safe for most people, but they raise the risk of side effects, including muscle aches, liver problems, mental fuzziness and the potential for developing diabetes.
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. ... Looking at data from 3,785 adults, ages 40 to 75 ...
The company produces and sells a variety of medicines, with 1,400 approved therapeutic molecules in its portfolio. [30] It owns brands (like Viagra , Xanax , Lipitor ), [ 6 ] [ 31 ] generics , including branded and complex generics, biosimilars , [ 32 ] [ 33 ] and over-the-counter (OTC) drugs and active pharmaceutical ingredients .
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