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Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases (mets).
The ability to invade surrounding tissue and metastasise is a hallmark of cancer.. The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities.
The dispersed tumors are called metastatic tumors, while the original is called the primary tumor. Almost all cancers can metastasize. [38] Most cancer deaths are due to cancer that has metastasized. [39] Metastasis is common in the late stages of cancer and it can occur via the blood or the lymphatic system or both. The typical steps in ...
The ability to invade surrounding tissue and metastasise is a hallmark of cancer.. The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities.
Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells.Cell division is a normal process used by the body for growth and repair.
A malignant tumor is defined by its capacity to initiate a biological phenomenon known as the metastatic cascade, a complex multi-stage process in which cell invasion precedes further cancer progression and the formation of metastases in distant organs and tissues. Massive metastatic lesions lead to the development of organ failure.
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The term benign in more general medical use characterizes a condition or growth that is not cancerous, i.e. does not spread to other parts of the body or invade nearby tissue. Sometimes the term is used to suggest that a condition is not dangerous or serious. [4] Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. [5]