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  2. Side-chain theory - Wikipedia

    en.wikipedia.org/wiki/Side-chain_theory

    The side-chain theory (German, Seitenkettentheorie) is a theory proposed by Paul Ehrlich (1854–1915) to explain the immune response in living cells.Ehrlich theorized from very early in his career that chemical structure could be used to explain why the immune response occurred in reaction to infection.

  3. Side chain - Wikipedia

    en.wikipedia.org/wiki/Side_chain

    In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called the "main chain" or backbone. The side chain is a hydrocarbon branching element of a molecule that is attached to a larger hydrocarbon backbone. It is one factor in determining a molecule's properties and reactivity. [2 ...

  4. Side-chain - Wikipedia

    en.wikipedia.org/wiki/Side-chain

    Side-chain, side chain, or sidechain may refer to: Side chain, a chemical group attached to the main chain or backbone of a molecule, such as a protein; Substituent, an atom or group of atoms substituted in place of a hydrogen atom on the parent chain of a hydrocarbon; Side-chaining, an effect in digital audio processing

  5. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    Then the cell stops producing all other side chains and starts intensive synthesis and secretion of the antigen-binding side chain as a soluble antibody. Though distinct from clonal selection, Ehrlich's idea was a selection theory far more accurate than the instructive theories that dominated immunology in the next decades.

  6. Glycine - Wikipedia

    en.wikipedia.org/wiki/Glycine

    Glycine (symbol Gly or G; [6] / ˈ ɡ l aɪ s iː n / ⓘ) [7] is an amino acid that has a single hydrogen atom as its side chain. It is the simplest stable amino acid (carbamic acid is unstable). Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). [8]

  7. Magic bullet (medicine) - Wikipedia

    en.wikipedia.org/wiki/Magic_bullet_(medicine)

    This led him to propose a new concept called "side-chain theory". (Later in 1900, he revised his concept as "receptor theory".) Based on his new theory, he postulated that in order to kill microbes, "wir müssen chemisch zielen lernen" ("we have to learn how to aim chemically"). [11] His institute was convenient as it was adjacent to a dye factory.

  8. Post-translational modification - Wikipedia

    en.wikipedia.org/wiki/Post-translational...

    oxidation: addition of one or more Oxygen atoms to a susceptible side-chain, principally of Met, Trp, His or Cys residues. Formation of disulfide bonds between Cys residues. pegylation: covalent attachment of polyethylene glycol (PEG) using a pegylation reagent, typically to the N-terminus or the side-chains of Lys residues. Pegylation is used ...

  9. Glycosylation - Wikipedia

    en.wikipedia.org/wiki/Glycosylation

    O-linked glycans attached to the hydroxyl oxygen of serine, threonine, tyrosine, hydroxylysine, or hydroxyproline side-chains, or to oxygens on lipids such as ceramide. Phosphoglycans linked through the phosphate of a phosphoserine. C-linked glycans, a rare form of glycosylation where a sugar is added to a carbon on a tryptophan side-chain.