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Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
Throughout adulthood, androgens and FSH cooperatively act on Sertoli cells in the testes to support sperm production. [10] Exogenous androgen supplements can be used as a male contraceptive. Elevated androgen levels caused by use of androgen supplements can inhibit production of LH and block production of endogenous androgens by Leydig cells.
The testicles are two gonads that produce sperm by meiotic division of germ cells within the seminiferous tubules, [1] and synthesize and secrete androgens that regulate the male reproductive functions. The site of production of androgens is the Leydig cells that are located in the interstitium between seminiferous tubules. [1]
Its primary functions are the production of sperm and the secretion of androgens, primarily testosterone. The release of testosterone is regulated by luteinizing hormone (LH) from the anterior pituitary gland .
Progesterone is the most important and only naturally occurring human progestogen. In general, androgens are considered "male sex hormones", since they have masculinizing effects, while estrogens and progestogens are considered "female sex hormones" although all types are present in each sex at different levels. [6] Sex hormones include ...
The spermatids are transformed into spermatozoa (sperm) by the process of spermiogenesis. These develop into mature spermatozoa, also known as sperm cells. [2] Thus, the primary spermatocyte gives rise to two cells, the secondary spermatocytes, and the two secondary spermatocytes by their subdivision produce four spermatozoa and four haploid ...
When an egg and sperm fuse at fertilization, the two sets of chromosomes come together to form a unique diploid individual with 46 chromosomes. [2] The sex chromosome in a human egg is always an X chromosome since a female only has X sex chromosomes. In sperm, about half the sperm have an X chromosome and half have a Y chromosome. [2]
Spermatogenesis is controlled by androgens, namely testosterone and follicle-stimulating hormone (FSH), these are the most important androgens that control the process. FSH uses very specific G-coupled receptors that can be found only on Sertoli cells, this hormone is secreted by the pituitary gland, located in the brain.