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Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
Syringe designed saline drops (e.g. Wallace Cameron Ultra Saline Minipod) are distributed in modern needle-exchange programmes as they can be used efficiently either by injection or ophthalmic (if the drug is potent in small doses) route of administer which is compared to intravenous use; by demonstration, the elimination of latanoprost acid ...
The 0.03% solution was applied topically once a day for eight months and showed "increased hair growth and thickening of the eyebrow hairs". Bimatoprost and its endogenous analog prostaglandin F2α ethanolamide present the side-effect of being anti-adipogenic, and have been shown to be inducers of preadipocyte proliferation.
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) [2] marketed in the US as an ophthalmic solution (brand names Prolensa and Bromday, [3] prior formulation brand name Xibrom, which has since been discontinued) by ISTA Pharmaceuticals for short-term, local use. Prolensa and Bromday are the once-daily formulation of bromfenac, while ...
Netarsudil, sold under the brand name Rhopressa among others, is a medication for the treatment of glaucoma. [1] [2] [3] In the United States, in December 2017, the Food and Drug Administration (FDA) approved a 0.02% ophthalmic solution for the lowering of elevated intraocular pressure in people with open-angle glaucoma or ocular hypertension.
Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis. [1] In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [2] [3]
It is unclear if use during pregnancy is safe for the fetus. [5] Tropicamide is in the antimuscarinic part of the anticholinergic family of medications. [3] It works by making the muscles within the eye unable to respond to nerve signals. [3] Tropicamide was approved for medical use in the United States in 1960. [3]
[5] [4] Use in pregnancy appears to be safe. [5] [4] When applied to the eye it works by decreasing the amount of aqueous humor made while increasing the amount that drains from the eye. [4] When applied to the skin it works by causing blood vessels to contract. [5] Brimonidine was patented in 1972 and came into medical use in 1996. [7]