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  2. Response evaluation criteria in solid tumors - Wikipedia

    en.wikipedia.org/wiki/Response_Evaluation...

    Today, the majority of clinical trials evaluating cancer treatments for objective response in solid tumors use RECIST. These criteria were developed and published in February 2000, and subsequently updated in 2009. The criteria are specifically not meant to determine whether patients have improved or not, as these are tumor-centric, not patient ...

  3. PET response criteria in solid tumors - Wikipedia

    en.wikipedia.org/wiki/PET_response_criteria_in...

    PET response criteria in solid tumors (PERCIST) is a set of rules that define when tumors in cancer patients improve ("respond"), stay the same ("stabilize"), or worsen ("progress") during treatment, using positron emission tomography (PET). The criteria were published in May 2009 in the Journal of Nuclear Medicine (JNM). [1]

  4. Immune-related response criteria - Wikipedia

    en.wikipedia.org/wiki/Immune-Related_Response...

    The immune-related response criteria (irRC) is a set of published rules that define when tumors in cancer patients improve ("respond"), stay the same ("stabilize"), or worsen ("progress") during treatment, where the compound being evaluated is an immuno-oncology drug.

  5. Tumor antigen - Wikipedia

    en.wikipedia.org/wiki/Tumor_antigen

    Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy. The field of cancer immunology studies such topics.

  6. Clinical endpoint - Wikipedia

    en.wikipedia.org/wiki/Clinical_endpoint

    The response rate is the percentage of patients on whom a therapy has some defined effect; for example, the cancer shrinks or disappears after treatment. [ 9 ] When used as a clinical endpoint for trials of cancer treatments, this is often called the objective response rate (ORR).

  7. Grading (tumors) - Wikipedia

    en.wikipedia.org/wiki/Grading_(tumors)

    Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia ).

  8. Diffuse large B-cell lymphoma - Wikipedia

    en.wikipedia.org/wiki/Diffuse_large_B-cell_lymphoma

    Diffuse large B-cell lymphoma (DLBCL) is a cancer of B cells, a type of lymphocyte that is responsible for producing antibodies.It is the most common form of non-Hodgkin lymphoma among adults, [1] with an annual incidence of 7–8 cases per 100,000 people per year in the US and UK.

  9. Common Terminology Criteria for Adverse Events - Wikipedia

    en.wikipedia.org/wiki/Common_Terminology...

    The Common Terminology Criteria for Adverse Events (CTCAE), [1] formerly called the Common Toxicity Criteria (CTC or NCI-CTC), are a set of criteria for the standardized classification of adverse events of drugs and treatment used in cancer therapy. The CTCAE system is a product of the US National Cancer Institute (NCI).