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Doctors use ketamine off-label to treat several conditions, ... Due to the risks of certain side effects of the drug, including abuse and misuse, a person must administer the nasal spray in a ...
Here, we explore ketamine therapy’s safety with Steven L. Mandel, M.D., co-founder of Ketamine Clinics Los Angeles and the founder of the nonprofit American Society of Ketamine Physicians ...
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [11] [13] is the S(+) enantiomer of ketamine. [6] [14] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
Side effects such as dissociation aren’t as worrisome in a medical setting when ketamine is infused, because “healthcare professionals will be ensuring that patients are not moving around ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
While S-ketamine is more effective as an analgesic and anesthetic through NMDA receptor antagonism, R-ketamine produces longer-lasting effects as an antidepressant. [19] The optical rotation of a given enantiomer of ketamine can vary between its salts and free base form.
Feifel, a professor emeritus of psychiatry at the University of California, San Diego’s School of Medicine, was one of the first doctors to use ketamine off-label to treat depression at the ...
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.