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Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Morphea is a form of scleroderma that is more common in women than men, in a ratio 3:1. [17] Morphea occurs in childhood as well as in adult life. [ 3 ] Morphea is an uncommon condition that is thought to affect 2 to 4 in 100,000 people. [ 18 ]
Papular mucinosis (also known as scleromyxedema, [1] [2] "generalized lichen myxedematosus" and "sclerodermoid lichen myxedematosus") is a rare skin disease. Localized and disseminated cases are called papular mucinosis or lichen myxedematosus while generalized, confluent papular forms with sclerosis are called scleromyxedema.
Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.
Here are some symptoms everyone should be aware of: Rashes You may not think of your skin as an organ, but it is — and it can be affected by inflammation just like any other organ.
Intestinal infections, such as gastroenteritis, can cause localized pain, often accompanied by nausea, vomiting, or diarrhea. Gastroenteritis, often called the “ stomach flu ,” is an infection ...
Treatment of sclerodactyly is by physical therapy, phototherapy, surgery, topical corticosteroids or vitamin D analogues, and systemic immunosuppressive drugs when the condition is part of systemic scleroderma [citation needed]. Localized treatment won't halt systemic disease, but can restore function and cosmetic aspects of the affected digits.
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
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