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Cholecystitis causes the gallbladder to become distended and firm. Distension can lead to decreased blood flow to the gallbladder, causing tissue death and eventually gangrene. [13] Once tissue has died, the gallbladder is at greatly increased risk of rupture (perforation), which can cause sharp pain.
It can cause inflammation to any part or layer of your bowel, although most often, it affects the end of your small bowel to the beginning of your colon, per Mayo Clinic. When Crohn’s is left ...
While the exact cause or causes are unknown, Crohn's disease seems to be due to a combination of environmental factors and genetic predisposition. [102] Crohn's is the first genetically complex disease in which the relationship between genetic risk factors and the immune system is understood in considerable detail. [ 103 ]
Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...
The exact cause of primary sclerosing cholangitis is unknown, and its pathogenesis is improperly understood. [1] Although PSC is thought to be caused by autoimmune disease, it does not demonstrate a clear response to immunosuppressants. Thus, many experts believe it to be a complex, multifactorial (including immune-mediated) disorder and ...
About 10% of cases have a more serious cause including gallbladder (gallstones or biliary dyskinesia) or pancreas problems (4%), diverticulitis (3%), appendicitis (2%) and cancer (1%). [2] More common in those who are older, ischemic colitis, [5] mesenteric ischemia, and abdominal aortic aneurysms are other serious causes. [6]
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