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Yellow nail syndrome, also known as "primary lymphedema associated with yellow nails and pleural effusion", [1]: 849 is a very rare medical syndrome that includes pleural effusions, lymphedema (due to under development of the lymphatic vessels) and yellow dystrophic nails. [2] Approximately 40% will also have bronchiectasis.
Onychauxis presents with thickened nails without deformity, and this simple thickening may be the result of trauma, acromegaly, Darier's disease, psoriasis, or pityriasis rubra pilaris, or, in some cases, hereditary. [1]: 783 [2] It may appear as loss of nail palate translucency, discoloration, and subungual hyperkeratosis.
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