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G6PD converts G6P into 6-phosphoglucono-δ-lactone and is the rate-limiting enzyme of the pentose phosphate pathway. Thus, regulation of G6PD has downstream consequences for the activity of the rest of the pentose phosphate pathway. Glucose-6-phosphate dehydrogenase is stimulated by its substrate G6P.
G6PD deficiency results from mutations in the G6PD gene. G6PD gene contributes to the production of glucose-6-phosphate dehydrogenase. Chemical reactions involving glucose-6-phosphate dehydrogenase produce compounds that prevent reactive oxygen species from building up to toxic levels within red blood cells. If a reduction in the amount of ...
People suffering from 6PGD or G6PD deficiency (or both) are at risk of hemolytic anemia in states of oxidative stress. Oxidative stress can result from infection and from chemical exposure to medication and certain foods. Broad beans, e.g., fava beans, contain high levels of vicine, divicine, convicine and isouramil, all of which are oxidants.
The National Principles (Malay: Rukun Negara; Jawi: روکون نݢارا ) is the Malaysian declaration of national philosophy instituted by royal proclamation on Merdeka Day, 1970, in reaction to the 13 May race riots, which occurred in 1969. [1]
The programme was handled by the National Service Training Department, or Jabatan Latihan Khidmat Negara (JLKN) under the Minister of Defence (MINDEF). The conscripts are 18-year-old youths that are selectively drafted. The three-month program, which started in December 2003, began as way to encourage friendship between youths of certain ages ...
The Bangsa Malaysia (English: Malaysian nation) policy was introduced by Prime Minister Mahathir Mohamad, to create an inclusive national identity for all inhabitants of Malaysia, thus abandoning the National Culture Policy that asserted a Malay ethnic national identity.
Malaysia Madani (English: Civilised Malaysia) [1] is a policy framework and government slogan introduced by the administration of the 10th Prime Minister, Anwar Ibrahim. [2] ...
Istana Negara with Kuala Lumpur skyline in the background at dusk in 2024. The site where the palace is located was gazetted for such purpose in 1976, and numerous contractors were involved in the initial planning. The need for a new palace, according to the Works Minister Samy Vellu, had been pressing due to space constraints in the old palace.