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Fowler's syndrome (urethral sphincter relaxation disorder) is a rare disorder in which the urethral sphincter fails to relax to allow urine to be passed normally in younger women with abnormal electromyographic activity detected.
It is a strap-like, C-shaped muscle at the base of the throat, behind the larynx. The upper esophageal sphincter encircles the proximal (upper) opening of the oesophagus. [9] The upper esophageal sphincter has a residual tone which is in fact augmented as it is stretched open. [10] Swallowing of air during eating and drinking is normal.
Lateral internal sphincterotomy is the preferred method of surgery for persons with chronic anal fissures, and is generally used when medical therapy has failed. [1] It is associated with a lower rate of side effects than older techniques such as posterior internal sphincterotomy and anoplasty, [3] and has also been shown to be superior to topical glyceryl trinitrate (GTN 0.2% ointment) in ...
A urethral bulking injection is one type of treatment for incontinence in women. Urethral bulking injections are considered by a clinician when the woman has urinary sphincter dysfunction, urethral hypermobility, persistent stress urinary incontinence after a urethral sling or urethropexy, or stress urinary incontinence in women who cannot undergo surgery due to other illnesses or conditions.
Botulinum toxin (botox) may be injected into the lower esophageal sphincter to paralyze the muscles holding it shut. As in the case of cosmetic botox, the effect is only temporary and lasts about 6 months. Botox injections cause scarring in the sphincter which may increase the difficulty of later Heller myotomy.
According to Sundar, “on average, Botox lasts three to four months,” so some women will conceive with Botox still in their systems. Other women will receive injections early in pregnancy ...
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
In males, the internal urethral sphincter has the additional function of preventing the flow of semen into the male bladder during ejaculation. [3] Females do have a more elaborate external sphincter muscle than males as it is made up of three parts: the sphincter urethrae, the urethrovaginal muscle, and the compressor urethrae.
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