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  2. Intrahepatic cholestasis of pregnancy - Wikipedia

    en.wikipedia.org/wiki/Intrahepatic_cholestasis...

    This, plus pruritus of palms and soles, could be considered as potentially diagnostic of ICP but only with elevated bile acid levels (however LFTs are not always elevated in ICP patients). The serum bile acid blood test for ICP is a quantitative measurement of bile acids. Other problems with the liver that occur in pregnancy should be ...

  3. Maternal physiological changes in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Maternal_physiological...

    Illustration of fundal height at various points during pregnancy. Some degree of weight gain is expected during pregnancy. The enlarging uterus, growing fetus, placenta, amniotic fluid, normal increase in body fat, and increase in water retention all contribute weight gain during pregnancy. The amount of weight gain can vary from 5 pounds (2.3 ...

  4. Bile acid - Wikipedia

    en.wikipedia.org/wiki/Bile_acid

    Activation of FXR in the liver inhibits synthesis of bile acids, and is one mechanism of feedback control when bile acid levels are too high. Secondly, FXR activation by bile acids during absorption in the intestine increases transcription and synthesis of FGF19, which then inhibits bile acid synthesis in the liver. [20]

  5. Cholestasis - Wikipedia

    en.wikipedia.org/wiki/Cholestasis

    Cholestasis is a condition where the flow of bile from the liver to the duodenum is impaired. [1] The two basic distinctions are: [1] obstructive type of cholestasis, where there is a mechanical blockage in the duct system that can occur from a gallstone or malignancy, and

  6. Cholestatic pruritus - Wikipedia

    en.wikipedia.org/wiki/Cholestatic_pruritus

    Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.

  7. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    When the total serum bilirubin increases over 95th percentile for age during the first week of life for high risk babies, it is known as hyperbilirubinemia of the newborn (neonatal jaundice) and requires light therapy to reduce the amount of bilirubin in the blood. Pathological jaundice in newborns should be suspected when the serum bilirubin ...

  8. Why Bill Gates Is Telling All About Life Before His Billions ...

    www.aol.com/why-bill-gates-telling-life...

    Microsoft founder Bill Gates is telling his “origin story” in his own words with the memoir Source Code, being released on Feb. 4 "My parents and early friends put me in a position to have a ...

  9. Hyperbilirubinemia in adults - Wikipedia

    en.wikipedia.org/wiki/Hyperbilirubinemia_in_adults

    Gallstones are more common in pregnant women due to elevated hormones and cholesterol levels, which block the bile duct and obstruct bilirubin excretion. [11] Besides, preeclampsia and eclampsia, denoted by high blood pressure, are linked to hyperbilirubinemia through damaging highly perfused organs, particularly liver and kidneys. [12]