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Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma [7] or rodent ulcer, [8] is the most common type of skin cancer. [2] It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it . [ 1 ]
Infiltrating basal cell carcinoma, sclerosing; Basal cell carcinoma, morphoeic; Basal cell carcinoma, desmoplastic type; M8093/3 Basal cell carcinoma, fibroepithelial (C44._) Fibroepithelioma of Pinkus type; Fibroepithelial basal cell carcinoma, Pinkus type; Pinkus tumor; Fibroepithelioma, NOS; M8094/3 Basosquamous carcinoma (C44._) Mixed basal ...
The mortality rate of basal-cell and squamous-cell carcinoma is around 0.3%, causing 2000 deaths per year in the US. In comparison, the mortality rate of melanoma is 15–20% and it causes 6500 deaths per year. [67]: 29, 31 Even though it is much less common, malignant melanoma is responsible for 75% of all skin cancer-related deaths. [68]
Basal cell carcinoma account for approximately 8% of all vulvar cancers. It typically affects women in the 7th and 8th decade of life. [22] These tend to be slow-growing lesions on the labia majora but can occur anywhere on the vulva. Their behavior is similar to basal cell cancers in other locations.
First described in 1960 by Gorlin and Goltz, [5] NBCCS is an autosomal dominant condition that can cause unusual facial appearances and a predisposition for basal-cell carcinoma, a type of skin cancer which rarely spreads to other parts of the body. The prevalence is reported to be 1 case per 56,000–164,000 population.
Of six patients with a facial basal cell carcinoma, treated with a 1% eosin solution and long-term exposure either to sunlight or arc-lamp light, four patients showed total tumour resolution and a relapse-free period of 12 months. [48]
Cutaneous squamous-cell carcinoma is the second-most common cancer of the skin (after basal-cell carcinoma, but more common than melanoma). It usually occurs in areas exposed to the sun. Sunlight exposure and immunosuppression are risk factors for SCC of the skin, with chronic sun exposure being the strongest environmental risk factor. [26]
Severe dysplasia / carcinoma in situ HPV-negative lesion with atypical keratinocytes in the basal cell layer WHO 2003 [3] Vulvar intraepithelial neoplasia (VIN) 1: VIN 2: VIN 3: VIN 3 WHO 2014 and ISSVD 2015 [3] Low-grade squamous intraepithelial lesion (LSIL) High-grade squamous intraepithelial lesion (HSIL) Intraepithelial neoplasia ...