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A palindromic sequence is a nucleic acid sequence in a double-stranded DNA or RNA molecule whereby reading in a certain direction (e.g. 5' to 3') on one strand is identical to the sequence in the same direction (e.g. 5' to 3') on the complementary strand. This definition of palindrome thus depends on complementary strands being palindromic of ...
There are also palindromic names in fictional media. "Stanley Yelnats" is the name of the main character in Holes, a 1998 novel and 2003 film. Five of the fictional Pokémon species have palindromic names in English (Eevee, Girafarig, Farigiraf, Ho-Oh, and Alomomola), as does the region Alola.
The intervening sequence of nucleotides between the initial sequence and the reverse complement can be any length including zero. For example, 5'---TTACGnnnnnn CGTAA---3' is an inverted repeat sequence. When the intervening length is zero, the composite sequence is a palindromic sequence. [2]
In genetics, dyad symmetry refers to two areas of a DNA strand whose base pair sequences are inverted repeats of each other. They are often described as palindromes.. For example, the following shows dyad symmetry between sequences GAATAC and GTATTC which are reverse complements of each other.
Non-palindromic numbers can be paired with palindromic ones via a series of operations. First, the non-palindromic number is reversed and the result is added to the original number. If the result is not a palindromic number, this is repeated until it gives a palindromic number. Such number is called "a delayed palindrome".
For example, the common restriction enzyme EcoRI recognizes the palindromic sequence GAATTC and cuts between the G and the A on both the top and bottom strands. This leaves an overhang (an end-portion of a DNA strand with no attached complement) known as a sticky end [2] on each end of AATT.
These are known as palindromic (P) nucleotides due to the palindromic nature of the sequence produced when DNA repair enzymes resolve the overhang. [18] The process of hairpin opening by Artemis is a crucial step of V(D)J recombination and is defective in the severe combined immunodeficiency (scid) mouse model .
For example, there are two PstI recognition sites in the following DNA sequence fragment, starting at base 9 and 31 respectively. A recognition sequence is a specific sequence, usually very short (less than 10 bases). Depending on the degree of specificity of the protein, a DNA-binding protein can bind to more than one specific sequence.