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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
Phages fd, f1, M13 and other related phages are Ff phages, for F specific (they infect Escherichia coli carrying the F-episome) filamentous phages, using the concept of vernacular name. [45] Filamentous bacteriophage engineered to display immunogenic peptides are useful in immunology and wider biological applications.
Phage typing is a phenotypic method that uses bacteriophages ("phages" for short) for detecting and identifying single strains of bacteria. [1] Phages are viruses that infect bacteria and may lead to bacterial cell lysis. [2] The bacterial strain is assigned a type based on its lysis pattern. [3]
Integration of prophages into the bacterial host is the characteristic step of the lysogenic cycle of temperate phages. Prophages remain latent in the genome through multiple cell divisions until activation by an external factor, such as UV light, leading to production of new phage particles that will lyse the cell and spread.
Adsorption is a value characteristic of phage-host pair and the adsorption of the phage on host cell surface is illustrated as a 2-stage process: reversible and irreversible. It involves the phages tail structure that begins when the phages tail fibers helps bind the phage to the appropriate receptor of its host. This process is reversible.
As there exist estimates of bacterial numbers on Earth of approximately 10 30, [4] there consequently is an expectation that 10 31 or more individual virus (mostly phage [5]) particles exist , making phages the most numerous category of "organisms" on our planet.
This genetic material uses the host cell's ribosomes to replicate, and synthesize proteins for the capsid and tail of the phage. New phages are assembled within the cell until the cellular membrane lyses (splits open). The newly made phages are now free to attack more cells. This process is known as the Lytic cycle. [3]
A Bacillus phage is a member of a group of bacteriophages known to have bacteria in the genus Bacillus as host species. These bacteriophages have been found to belong to the families Myoviridae, Siphoviridae, Podoviridae, or Tectiviridae.