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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the secondary messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals.
The database is distributed as a plain text file with one entry to a line in the format "WORD <pronunciation>" with a two-space separator between the parts. If multiple pronunciations are available for a word, variants are identified using numbered versions (e.g. WORD(1)).
This is the pronunciation key for IPA transcriptions of Spanish on Wikipedia. It provides a set of symbols to represent the pronunciation of Spanish in Wikipedia articles, and example words that illustrate the sounds that correspond to them.
The cognates in the table below share meanings in English and Spanish, but have different pronunciation. Some words entered Middle English and Early Modern Spanish indirectly and at different times. For example, a Latinate word might enter English by way of Old French, but enter Spanish directly from Latin. Such differences can introduce ...
The Diccionario de la lengua española [a] (DLE; [b] English: Dictionary of the Spanish language) is the authoritative dictionary of the Spanish language. [1] It is produced, edited, and published by the Royal Spanish Academy, with the participation of the Association of Academies of the Spanish Language.
Phosphodiesterase enzymes have been shown to be different in different types of cells, including normal and leukemic lymphocytes [11] and are often targets for pharmacological inhibition due to their unique tissue distribution, structural properties, and functional properties.
Phosphodiesterase 1, PDE1, EC 3.1.4.1, systematic name oligonucleotide 5 ′-nucleotidohydrolase) is a phosphodiesterase enzyme also known as calcium- and calmodulin-dependent phosphodiesterase. It is one of the 11 families of phosphodiesterase (PDE1-PDE11).
The z in the Spanish word chorizo is sometimes realized as / t s / by English speakers, reflecting more closely the pronunciation of the double letter zz in Italian and Italian loanwords in English. This is not the pronunciation of present-day Spanish, however. Rather, the z in chorizo represents or (depending on dialect) in Spanish.