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Local anesthetic injections are given in specific areas of the mouth, rather than the whole body. Although several different medications are available, the most commonly used local anesthetic to prevent pain in the area around a tooth is lidocaine (also called xylocaine or lignocaine). Lidocaine's half-life in the body is about 1.5–2 hours. [2]
Lidocaine is an antiarrhythmic medication of the class Ib type. [7] This means it works by blocking sodium channels thus decreasing the rate of contractions of the heart. [10] [7] When injected near nerves, the nerves cannot conduct signals to or from the brain. [8] Lidocaine was discovered in 1946 and went on sale in 1948. [11]
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by APP Pharmaceuticals under the trade name EMLA (an abbreviation for Eutectic Mixture of Local Anesthetics ). [ 5 ]
Unilever Philippines, Inc. is the Philippine subsidiary of British multinational consumer goods company Unilever.It is based in Bonifacio Global City, Taguig since 2016. It is a manufacturer of laundry detergents and soaps, shampoos and hair conditioners, toothpastes, deodorants, skin care products, household cleaners, and toilet soaps with an annual sales of over 40 billion pesos.
Investor appetite will be sorely tested this week by the sale of $119 billion in new three-, 10- and 3-year Treasuries. The steady climb in yields kept the dollar index up at 108.870, having risen ...
[2] [3] In 2012, the United Nations said the Philippines had the highest rate of methamphetamine use in East Asia, and according to a U.S. State Department report, 2.1 percent of Filipinos aged 16 to 64 use the drug [4] based on 2008 figures by the Philippines Dangerous Drugs Board. [5]
Laguna [lɐˈɣuː.na], officially the Province of Laguna (Filipino: Lalawigan ng Laguna), is a province in the Philippines located in the Calabarzon region in Luzon.Its capital is Santa Cruz while its largest city is the City of Calamba (the regional center of Calabarzon) and the province is situated southeast of Metro Manila, south of the province of Rizal, west of Quezon, north of Batangas ...