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A combination of dipyridamole and aspirin (acetylsalicylic acid/dipyridamole) is FDA-approved for the secondary prevention of stroke and has a bleeding risk equal to that of aspirin use alone. [4] Dipyridamole absorption is pH-dependent and concomitant treatment with gastric acid suppressors (such as a proton pump inhibitor) will inhibit the ...
The combination drug acetylsalicylic acid/dipyridamole (trade names Aggrenox, Asasantin) is a drug combination of: [1] Dipyridamole, a drug that inhibits platelet activation [2] when given chronically and causes vasodilation when given at high doses over short time. The combination acts as an extended release formulation and is primarily used ...
Antiplatelet drug. An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation [1] and inhibit thrombus formation. They are effective in the arterial circulation where classical Vitamin K antagonist ...
In the US, ticagrelor is indicated to reduce the risk of stroke in people with acute ischemic stroke or high-risk transient ischemic attack. [5]In the EU, ticagrelor, co-administered with acetylsalicylic acid (aspirin), is indicated for the prevention of atherothrombotic events in adults with acute coronary syndromes or a history of myocardial infarction and a high risk of developing an ...
6.3 million (2015) [ 12 ] Stroke (also known as a cerebrovascular accident (CVA) or brain attack) is a medical condition in which poor blood flow to the brain causes cell death. [ 5 ] There are two main types of stroke: ischemic, due to lack of blood flow, and. hemorrhagic, due to bleeding.
1. Thus, the CHA 2 DS 2 -VASc score is a refinement of CHADS 2[8][10] score and extends the latter by including additional common stroke risk factors, that is, age 65–74, female gender and vascular disease. [11] In the CHA 2 DS 2 -VASc score, 'age 75 and above' also has extra weight, with 2 points. The maximum CHADS 2 score is 6, whilst the ...