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A combination of dipyridamole and aspirin (acetylsalicylic acid/dipyridamole) is FDA-approved for the secondary prevention of stroke and has a bleeding risk equal to that of aspirin use alone. [4] Dipyridamole absorption is pH-dependent and concomitant treatment with gastric acid suppressors (such as a proton pump inhibitor) will inhibit the ...
The combination drug acetylsalicylic acid/dipyridamole (trade names Aggrenox, Asasantin) is a drug combination of: [1] Dipyridamole, a drug that inhibits platelet activation [2] when given chronically and causes vasodilation when given at high doses over short time. The combination acts as an extended release formulation and is primarily used ...
After TIA or minor stroke, aspirin therapy has been shown to reduce the short-term risk of recurrent stroke by 60–70%, and the long-term risk of stroke by 13%. [24] The typical therapy may include aspirin alone, a combination of aspirin plus extended-release dipyridamole, or clopidogrel alone. [21]
Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...
Adenosine diphosphate (ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke. These drugs antagonize the P2Y 12 platelet receptors and therefore prevent the binding of ...
Ticlopidine, sold under the brand name Ticlid, is a medication used to reduce the risk of thrombotic strokes. [1] It is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. Research initially showed that it was useful for preventing strokes and coronary stent occlusions.
Antiplatelet drug. An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation [1] and inhibit thrombus formation. They are effective in the arterial circulation where classical Vitamin K antagonist ...
aspirin: antiplatelet risks for GI tract bleeding and hemorrhagic stroke [40] [41] [32] [42] [43] dipyridamole: platelet aggregation inhibitor oral or intravenous Abdominal or stomach cramps, diarrhea, dizziness or lightheadedness [44] [45] [46] [41] clopidogrel: antiplatelet [45] [41] ticlid: enoxaparin: anticoagulant