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Long-term exposure to MDMA in humans has been shown to produce marked neurodegeneration in striatal, ... Sympathomimetic side effects can be managed with carvedilol.
[81] [82] Concerns regarding the long-term effects of benzodiazepines have been raised since 1980. [83] These concerns are still not fully answered. A review in 2006 of the literature on use of benzodiazepine and nonbenzodiazepine hypnotics concluded that more research is needed to evaluate the long-term effects of hypnotic drugs. [84]
[3] [4] [5] Methamphetamine psychosis, or long-term effects of stimulant use in the brain (at the molecular level), depend upon genetics and may persist for months or years. [6] Psychosis may also result from withdrawal from stimulants, particularly when psychotic symptoms were present during use. [7]
A 2019 double-blind study administered both MDA and MDMA to healthy volunteers. The study found that MDA shared many properties with MDMA including entactogenic and stimulant effects, but generally lasted longer and produced greater increases in psychedelic-like effects like complex imagery, synesthesia, and spiritual experiences. [2]
25I-NBOMe (2C-I-NBOMe, Cimbi-5, and also shortened to "25I"), also known as Smiles, or N-Bomb, is a novel synthetic psychoactive substance with strong hallucinogenic properties, synthesized in 2003 for research purposes.
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
6 Potential Long-Term Effects of Ozempic. You may have heard about — or maybe even experienced — the short-term side effects of Ozempic® — such as nausea, vomiting, constipation, and diarrhea.
The effects of DOM were assessed in clinical studies in the late 1960s and early 1970s and by other researchers. [ 2 ] [ 7 ] [ 10 ] [ 11 ] [ 12 ] At low doses, such as 1 to 4 mg, DOM produces effects including stimulation , euphoria , enhanced self-awareness , and mild dose-dependent perceptual disturbances . [ 2 ]