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  2. MDMA - Wikipedia

    en.wikipedia.org/wiki/MDMA

    The effects established so far for recreational use of ecstasy lie in the range of moderate to severe effects for serotonin transporter reduction. [ 88 ] Impairments in multiple aspects of cognition, including attention, learning, memory, visual processing , and sleep, have been found in regular MDMA users.

  3. Ecstasy (emotion) - Wikipedia

    en.wikipedia.org/wiki/Ecstasy_(emotion)

    Ecstasy (from Ancient Greek ἔκστασις (ékstasis) 'outside of oneself') is a subjective experience of total involvement of the subject with an object of their awareness. In classical Greek literature , it refers to removal of the mind or body "from its normal place of function."

  4. 3,4-Methylenedioxyamphetamine - Wikipedia

    en.wikipedia.org/wiki/3,4-Methylenedioxyamphetamine

    A 2019 double-blind study administered both MDA and MDMA to healthy volunteers. The study found that MDA shared many properties with MDMA including entactogenic and stimulant effects, but generally lasted longer and produced greater increases in psychedelic-like effects like complex imagery, synesthesia, and spiritual experiences. [55]

  5. Hyperlocomotion - Wikipedia

    en.wikipedia.org/wiki/Hyperlocomotion

    [58] [57] [59] In addition, the α 1-adrenergic receptor antagonists prazosin and doxazosin reduce the psychostimulant and/or euphoric effects of MDMA in humans. [ 60 ] [ 61 ] [ 62 ] Similarly, the norepinephrine reuptake inhibitor (NRI) reboxetine , which prevents MDMA from inducing norepinephrine release, likewise reduces the stimulant ...

  6. Family posts shocking video of teen's brain damage after ...

    www.aol.com/news/2015-09-10-teen-posts-shocking...

    Thomson's family decided to post a video on Facebook of the teen in her current state. They want to warn others of the dangers that can occur when taking drugs.

  7. meta-Chlorophenylpiperazine - Wikipedia

    en.wikipedia.org/wiki/Meta-Chlorophenylpiperazine

    In comparison studies, mCPP has approximately 10-fold selectivity for the human 5-HT 2C receptor over the human 5-HT 2A and 5-HT 2B receptors (K i = 3.4 nM vs. 32.1 and 28.8 nM). [11] It acts as a partial agonist of the human 5-HT 2A [ 47 ] and 5-HT 2C [ 48 ] receptors but as an antagonist of the human 5-HT 2B receptors.

  8. MDMA-assisted psychotherapy - Wikipedia

    en.wikipedia.org/wiki/MDMA-assisted_psychotherapy

    Alexander Shulgin, an American chemist who helped publish the first report on the effects of MDMA in humans. MDMA was first synthesized by the German pharmaceutical company Merck KGaA in 1912 as an intermediate in the synthesis of a potential blood clotting medication. Its psychoactive effects were not noted until the early 1960s. In the 1970s ...

  9. Psychoactive drug - Wikipedia

    en.wikipedia.org/wiki/Psychoactive_drug

    Both legal and illegal, the consumption of drugs and their effects on the human body encompasses all aspects of sex, including desire, performance, pleasure, conception, gestation, and disease. There are many different types of drugs that are commonly associated with their effects on sex, including alcohol , cannabis , cocaine , MDMA , GHB ...