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Xenon Xe 129 hyperpolarized, sold under the brand name Xenoview, is a hyperpolarized contrast agent indicated for use with magnetic resonance imaging (MRI) for evaluation of lung ventilation, and approved for people aged twelve years of age and older. [4] [5] It was approved for medical use in the US in December 2022. [6]
In order to obtain images of the subject's lung tissue, the polarized xenon gas is inhaled through a tube connected to a mouthpiece. The subject is instructed to take a deep breath and exhale fully twice before inhaling the gas. The typical scan uses a mixture of 200-1000 ml of 129Xe and a buffer gas such as helium or nitrogen.
The hyperpolarization method called spin-exchange optical pumping (SEOP) is being used to hyperpolarize noble gases such as Xenon-129 and Helium-3. When an inhaled hyperpolarized gas like 3He or 129Xe is imaged, there is a higher magnetization density of NMR-active molecules in the lung compared to traditional 1H imaging, which improves the MRI ...
Biosensors used for screening combinatorial DNA libraries. In a biosensor, the bioreceptor is designed to interact with the specific analyte of interest to produce an effect measurable by the transducer. High selectivity for the analyte among a matrix of other chemical or biological components is a key requirement of the bioreceptor.
Xenon-136 is an isotope of xenon that undergoes double beta decay to barium-136 with a very long half-life of 2.11 × 10 21 years, more than 10 orders of magnitude longer than the age of the universe ((13.799 ± 0.021) × 10 9 years). It is being used in the Enriched Xenon Observatory experiment to search for neutrinoless double beta decay.
Electrochemical aptamer-based (E-AB) biosensors is a device that takes advantage of the electrochemical and biological properties of aptamers to take real time, in vivo measurements. An electrochemical aptamer-based (E-AB) biosensor generates an electrochemical signal in response to specific target binding in vivo [ 3 ] The signal is measured ...
Compared with solar xenon, Earth's atmospheric Xe is enriched in heavy isotopes by 3 to 4% per atomic mass unit (amu). [18] However, the total abundance of xenon gas is depleted by one order of magnitude relative to other noble gases. [15] The elemental depletion while relative enrichment in heavy isotopes is called the "Xenon paradox".
Biosensors International Group, Ltd. is a medical device company that specializes in developing, manufacturing and licensing technologies for use in interventional cardiology procedures and critical care. The company was listed on the mainboard of the Singapore Exchange (SGX) in May 2005.