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  2. Pathophysiology of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_HIV/AIDS

    This acute viremia is associated in virtually all people with the activation of CD8 + T cells, which kill HIV-infected cells, and subsequently with antibody production, or seroconversion. The CD8 + T cell response is thought to be important in controlling virus levels, which peak and then decline, as the CD4 + T cell counts rebound.

  3. HIV - Wikipedia

    en.wikipedia.org/wiki/HIV

    HIV infects vital cells in the human immune system, such as helper T cells (specifically CD4 + T cells), macrophages, and dendritic cells. [11] HIV infection leads to low levels of CD4 + T cells through a number of mechanisms, including pyroptosis of abortively infected T cells, [12] apoptosis of uninfected bystander cells, [13] direct viral ...

  4. CD4 - Wikipedia

    en.wikipedia.org/wiki/CD4

    HIV infection leads to a progressive reduction in the number of T cells expressing CD4. Medical professionals refer to the CD4 count to decide when to begin treatment during HIV infection, although recent medical guidelines have changed to recommend treatment at all CD4 counts as soon as HIV is diagnosed.

  5. HIV is no longer a death sentence. But why is a viable cure ...

    www.aol.com/hiv-no-longer-death-sentence...

    The HIV virus primarily infects one immune cell in our immune system called a T cell. And once it gets inside that cell, it becomes part of the person's DNA. ... as opposed to antivirals that ...

  6. HIV tropism - Wikipedia

    en.wikipedia.org/wiki/HIV_tropism

    Red cells are from monkeys infected with simian-human immunodeficiency virus, while blue cells are from uninfected ones. HIV tropism refers to the cell type in which the human immunodeficiency virus infects and replicates. HIV tropism of a patient's virus is measured by the Trofile assay. HIV can infect a variety of cells such as CD4+ helper T ...

  7. T helper cell - Wikipedia

    en.wikipedia.org/wiki/T_helper_cell

    These cells undergo abortive infection with HIV. [36] Cell death is triggered when the host cell detects HIV foreign DNA intermediates and initiates a suicidal death pathway in an attempt to protect the host, leading to caspase-1 activation in inflammasomes, thus causing pyroptosis (a highly inflammatory form of programmed cell death). [37] [38 ...

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