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Analgesic nephropathy is injury to the kidneys caused by analgesic medications such as aspirin, bucetin, phenacetin, and paracetamol. The term usually refers to damage induced by excessive use of combinations of these medications, especially combinations that include phenacetin. It may also be used to describe kidney injury from any single ...
Acute kidney injury. Pathologic kidney specimen showing marked pallor of the cortex, contrasting to the darker areas of surviving medullary tissue. The patient died with acute kidney injury. Acute kidney injury (AKI), previously called acute renal failure (ARF), [1][2] is a sudden decrease in kidney function that develops within 7 days, [3] as ...
Compared to other NSAIDs, it may have other side effects such as gastrointestinal bleeding. [10] Long-term use has been associated with kidney failure, and rarely liver failure, and it can exacerbate the condition of patients with heart failure. [8]
Loop diuretics may also precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor—the so-called "triple whammy" effect. [19] Because furosemide, torsemide and bumetanide are technically sulfa drugs, there is a theoretical risk that patients sensitive to sulfonamides may be sensitive to these loop diuretics. This ...
Kidney failure is especially a risk if the patient is also concomitantly taking an ACE inhibitor (which removes angiotensin II's vasoconstriction of the efferent arteriole) and a diuretic (which drops plasma volume, and thereby RPF)—the so-called "triple whammy" effect. [82] In rarer instances NSAIDs may also cause more severe kidney ...
Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. [8] The heart disease risk may be lower than with other NSAIDs. [8] It is not recommended in people with kidney problems. [8] Use is not recommended in the third trimester of pregnancy. [8] Naproxen is a nonselective COX ...
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