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The Schaffer collateral is located between the CA3 region and CA1 region in the hippocampus. Schaffer collaterals are the axons of pyramidal cells that connect two neurons (CA3 and CA1) and transfer information from CA3 to CA1. [5] [6] The entorhinal cortex sends the main input to the dentate gyrus (perforant pathway).
The Renshaw cells are ultimately excited by multiple antidromic motor neuron axons, where the majority of axons originate from synergist motor neurons, and in turn the Renshaw cell synapses with multiple neurons, eliciting IPSP in alpha motor, 1a inhibitory interneurons and gamma motor neurons. The antidromic collateral circuit back to the ...
The trisynaptic circuit is a neural circuit in the hippocampus, which is made up of three major cell groups: granule cells in the dentate gyrus, pyramidal neurons in CA3, and pyramidal neurons in CA1. The hippocampal relay involves 3 main regions within the hippocampus which are classified according to their cell type and projection fibers.
There are also a significant number of recurrent connections that terminate in CA3. Both the recurrent connections and the Schaffer collaterals terminate preferentially in the septal area in a dorsal direction from the originating cells. CA3 also sends a small set of output fibers to the lateral septum.
Anatomy of a multipolar neuron. A neural circuit is a population of neurons interconnected by synapses to carry out a specific function when activated. [1] Multiple neural circuits interconnect with one another to form large scale brain networks.
The types of neurons found in the stratum lucidum are called interneurons, [3] neurons which form a connection between other neurons in a different location. This situation is described in the mossy fiber axon connection in the CA3 stratum lucidum region of the hippocampus as is in relation to Purkinje cells .
This is the signal seen by an extracellular electrode placed in the layer of apical dendrites of CA1 pyramidal neurons. [8] The Schaffer collaterals make excitatory synapses onto these dendrites, and so when they are activated, there is a current sink in stratum radiatum: the field EPSP.
An axon, also called a nerve fiber, is a long, slender projection of a nerve cell that conducts electrical impulses called action potentials away from the neuron's cell body to transmit those impulses to other neurons, muscle cells, or glands.