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A medical triad is a group of three signs or symptoms, the result of injury to three organs, which characterise a specific medical condition. The appearance of all three signs conjoined together in another patient, points to that the patient has the same medical condition, or diagnosis.
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An example of a triad is Meltzer's triad presenting purpura a rash, arthralgia painful joints, and myalgia painful and weak muscles. Meltzer's triad indicates the condition cryoglobulinemia . Huntington's disease is a neurodegenerative disease that is characterized by a triad of motor, cognitive, and psychiatric signs and symptoms. [ 31 ]
In mammals, triads are typically located at the A-I junction; [1] that is, the junction between the A and I bands of the sarcomere, which is the smallest unit of a muscle fiber. Triads form the anatomical basis of excitation-contraction coupling , whereby a stimulus excites the muscle and causes it to contract.
Reynolds' pentad is a collection of signs and symptoms consistent with obstructive ascending cholangitis, a serious infection of the biliary tract.It is a combination of Charcot's triad (right upper quadrant pain, jaundice, and fever) with shock (low blood pressure, tachycardia) and an altered mental status. [1]
Mwakio's triad [ edit ] Is a clinical triad seen commonly in pelvic inflammatory disease(PID) which consist of 2 symptoms including lower abdominal pain of variable severity, purulent vaginal discharge and 1 clinical sign which is cervical motion tenderness on bimanual pelvic examination.
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In medicine, Garrod's tetrad is a term named for British physician Archibald Garrod, who introduced the phrase "inborn errors of metabolism" in a lecture in 1908. [ 1 ] The tetrad comprises four inherited metabolic diseases : albinism , alkaptonuria , cystinuria , and pentosuria .