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Treatment depends on the type of neurogenic bladder and other medical problems. Treatment strategies include catheterization , medications, surgeries or other procedures. The goals of treatment focus on preserving the structure and function of the upper urinary tract , and on improving the quality of life for patients with neurogenic bladder.
Bladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) [1] and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury [2] or multiple sclerosis [3] which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the ...
The efficacy of solifenacin to treat neurogenic detrusor overactivity (NDO) was established in two clinical trials with a total of 95 pediatric NDO participants, ages two to 17 years old. [2] The studies were designed to measure (as a primary efficacy endpoint) the maximum amount of urine the bladder could hold after 24 weeks of treatment. [2]
In men, prostate surgery (prostatectomy, TURP, etc) and radiation therapy can damage the sphincter and cause stress incontinence. [7] Neurogenic bladder dysfunction can involve a malfunctioning urethral sphincter. [8] Urge incontinence can happen when the urethra cannot hold the urine in as the bladder contracts uncontrollably. [9]
Treatment typically includes α1-receptor antagonists such as tamsulosin, which relaxes smooth muscle in the bladder neck, and 5α-reductase inhibitors like finasteride and dutasteride, which reduce prostate enlargement. Clinical trials have demonstrated that combining these medications improves urinary symptoms and lowers the likelihood of ...
Many studies have been initiated using the sacral nerve stimulation (SNS) technique to treat patients that suffer with urinary problems. [citation needed] When applying this procedure, proper patient screening is essential, because some disorders that affect the urinary tract (like bladder calculus or carcinoma in-situ) have to be treated differently.
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