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In the United States, about 2% of people have chronic hepatitis C. [16] In 2014, an estimated 30,500 new acute hepatitis C cases occurred (0.7 per 100,000 population), an increase from 2010 to 2012. [120] The number of deaths from hepatitis C rose to 15,800 in 2008 [121] having overtaken HIV/AIDS as a cause of death in the US in 2007. [122]
Hepatitis C virus (HCV) can cause acute and chronic infections that are a major cause of hepatocellular carcinoma (HCC), advanced hepatic fibrosis and cirrhosis. [citation needed] HCC is a major cause of death in patients with chronic HCV infection. Regarding the pathogenesis of HCC associated with HCV, that virus may play direct or indirect roles.
The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
Rarely, people with the hepatitis A virus can rapidly develop liver failure, termed fulminant hepatic failure, especially the elderly and those who had a pre-existing liver disease, especially hepatitis C. [17] [81] Mortality risk factors include greater age and chronic hepatitis C. [17] In these cases, more aggressive supportive therapy and ...
The list of conditions associated with chronic liver disease is extensive and can be categorised in the following way: [3] Viral causes. Hepatitis B; Hepatitis C; Cytomegalovirus (CMV), Epstein Barr virus (EBV), and yellow fever viruses cause acute hepatitis. Toxic and drugs. Alcoholic liver disease
The treatment for the HCV genotype also depends on the presence or absence of cirrhosis. [11] There are six major genotypes of hepatitis C virus which includes many subtypes. [12] The genotype can affect treatment of HCV infections. [3] Recent studies show that HCV genotypes consist of 8 genotypes and 67 subtypes.
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