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Hepatic artery thrombosis is the most common complication that occurs after liver transplantation. [2] Hepatic artery thrombosis may also occur after other surgeries. [2] Hepatic artery thrombosis and primary non-function are the two most common reason that a transplanted liver fails to work (graft failure). [3]
Liver transplantation is a potential treatment for acute or chronic conditions which cause irreversible and severe ("end-stage") liver dysfunction. [4] Since the procedure carries relatively high risks, is resource-intensive, and requires major life modifications after surgery, it is reserved for dire circumstances.
Liver damage can be caused by viruses, alcohol, medications, and other hepatotoxins. [12] Acetaminophen, found in many prescription and over-the-counter medications, is the most common drug that can cause liver damage if taken in a high dose or in conjunction with alcohol. [12] Many liver transplant patients require the transplant because of ...
If complications cannot be controlled or when the liver ceases functioning, liver transplantation is necessary. Survival from liver transplantation has been improving over the 1990s, and the five-year survival rate is now around 80%. The survival rate depends largely on the severity of disease and other medical risk factors in the recipient. [124]
Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80–90% of liver cells).
The risk of HCC recurrence after liver transplantation is less than 15%. [6] Macrovascular or extrahepatic spread (spread of the cancer to blood vessels or outside the liver, respectively) are contraindications to liver transplantation. [6] The risks of liver transplantation extend beyond risk of the procedure itself.
HRS is a relatively common complication of cirrhosis, occurring in 18% of people within one year of their diagnosis, and in 39% within five years of their diagnosis. Deteriorating liver function is believed to cause changes in the circulation that supplies the intestines, altering blood flow and blood vessel tone in the kidneys. The kidney ...
Budd–Chiari syndrome is a condition when an occlusion or obstruction in the hepatic veins prevent normal outflow of blood from the liver. The symptoms are non-specific and vary widely, but it may present with the classical triad of abdominal pain, ascites, and liver enlargement. Untreated Budd-Chiari syndrome can result in liver failure. [1]