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Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
The drugs have been in short supply since 2022, soon after the FDA approved Wegovy for weight loss purposes. Novo Nordisk said it made a $6.5 billion investment to increase production in the U.S.
Announcements and reports of future meetings pertaining to the activities of the Controlled Release Society are also included. According to the Journal Citation Reports, the journal has a 2022 impact factor of 10.8, ranking it 10th out of 275 in the category Pharmacology & Pharmacy. [1]
A 54 mg tablet of Concerta, which uses OROS technology. 22% of the drug is contained in the red overcoat, while the remaining 78% is split between two drug layers of differing concentration. The tablet uses an additional push layer that expands as water enters the tablet via the osmotic membrane.
Alogliptin, sold under the brand names Nesina and Vipidia, [2] [3] is an oral anti-diabetic drug in the DPP-4 inhibitor (gliptin) class. [4] Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of hypoglycemia, and has relatively modest glucose-lowering activity. [1]
The American Postal Workers Union (APWU) is a labor union in the United States. It represents over 200,000 employees and retirees of the United States Postal Service who belong to the Clerk, Maintenance, Motor Vehicle, and Support Services divisions. It also represents approximately 2,000 private-sector mail workers.
The products recommended for suspension included several 300 mg modified-release bupropion tablets. [197] Following EMA's call for an industry-wide review of medicines for the possible presence of nitrosamines, [198] GlaxoSmithKline paused batch release and distribution of bupropion 150 mg tablets in November 2022. In July 2023, EMA raised the ...
The review noted that the drug has a high therapeutic index, being used at initial oral doses ranging from 6 to 90 mg, and probably requires a 50% higher dose to induce the same demineralizing effect as prednisolone. Thus it has "a smaller impact on calcium metabolism than any other synthetic corticosteroid, and therefore shows a lower risk of ...