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15–50% (with sudden stopping) [3] [4] Antidepressant discontinuation syndrome , also called antidepressant withdrawal syndrome , is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [ 5 ]
Below are the common early side effects of taking sertraline, as well as the rarer, more serious side effects that you may encounter. This article also touches on the long-term side effect risk of ...
Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight gain you’ve ...
Like other SSRIs, sertraline is associated with sexual side effects, including sexual arousal disorder, erectile dysfunction and difficulty achieving orgasm. While nefazodone and bupropion do not have negative effects on sexual functioning, 67% of men on sertraline experienced ejaculation difficulties versus 18% before the treatment. [ 92 ]
Other theories involve the effects of antidepressants on receptor sites for acetylcholine, a key neurotransmitter that may play a role in appetite stimulation. Depression itself can also have an ...
Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertraline's (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 (σ 1) receptor in CNS. [18]
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