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High-grade prostatic intraepithelial neoplasia (HGPIN) is an abnormality of prostatic glands and believed to precede the development of prostate adenocarcinoma (the most common form of prostate cancer). [1] [2] It may be referred to simply as prostatic intraepithelial neoplasia (PIN).
Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [91] Prostate cancer is rare in those under 40 years old, [92] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [93]
Men over the age of 50 are more likely to experience an enlarged prostate
Things to avoid if you have symptoms of an enlarged prostate, according to the NHS in England [11]. Lifestyle alterations to address the symptoms of BPH include physical activity, [ 59 ] decreasing fluid intake before bedtime, moderating the consumption of alcohol and caffeine-containing products, and following a timed voiding schedule.
Diagnosis involves ruling out other potential causes of the symptoms such as bacterial prostatitis, benign prostatic hyperplasia, overactive bladder, and cancer. [2] [5] Recommended treatments include multimodal therapy, physiotherapy, and a trial of alpha blocker medication or antibiotics in certain newly diagnosed cases. [6]
The symptoms of an enlarged prostate can include frequent urination and needing to get up many times in the night to pee. A man might have trouble getting started in the bathroom or dribbling when ...