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There’s no best time to take metformin for weight loss or type 2 diabetes (or any other condition). ... Prepare for potential side effects. Taking metformin may cause unpleasant side effects ...
A 2017 review found that people with diabetes who were taking metformin had lower all-cause mortality. [231] They also had reduced cancer and cardiovascular disease compared with those on other therapies. [231] In people without diabetes, metformin does not appear to reduce the risk of cancer and cardiovascular disease. [237]
Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...
A smaller study on metformin also found that the average weight lost in 154 patients was between 5.6 and 7 kilograms ... These severe adverse effects of weight loss diabetes drugs are uncommon ...
However, diabetes does cause higher morbidity, mortality and operative risks with these conditions. [ 41 ] Diabetic foot, often due to a combination of sensory neuropathy (numbness or insensitivity) and vascular damage, increases rates of skin ulcers ( diabetic foot ulcers ) and infection and, in serious cases, necrosis and gangrene.
There are a few groups of people who shouldn’t take metformin. Before taking metformin, let your doctor know if you have any medical conditions like kidney or liver problems or type 1 diabetes ...