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Avalglucosidase alfa is composed of the human GAA enzyme that is conjugated with a couple of bis-mannose-6-phosphate (bis-M6P) tetra-mannose glycans. [12] The bis-MGP of avalglucosidase alpha binds to the cation-independent mannose-6-phosphate receptor which is located on the skeletal muscles. [12]
As of 2023, Mayo Clinic Hospital in Arizona has been ranked No.1 in Arizona and the Phoenix metro area as part of U.S. News & World Report’s “Best Hospitals” rankings. In addition, for a sixth consecutive year, Mayo Clinic in Arizona was recognized on the "Best Hospitals Honor Roll" which recognizes the top 20 hospitals in the nation. [13]
Mayo Clinic is a nonprofit hospital system with campuses in Rochester, Minnesota; Scottsdale and Phoenix, Arizona; and Jacksonville, Florida. [22] [23] Mayo Clinic employs 76,000 people, including more than 7,300 physicians and clinical residents and over 66,000 allied health staff, as of 2022. [5]
Alglucosidase alfa, sold under the brand name Myozyme among others, is an enzyme replacement therapy (ERT) orphan drug for treatment of Pompe disease (Glycogen storage disease type II), a rare lysosomal storage disorder (LSD). [6] Chemically, the drug is an analog of the enzyme that is deficient in patients affected by Pompe disease, alpha ...
Banner - University Medical Center Phoenix (BUMCP; formerly Banner Good Samaritan Medical Center or "Good Sam") is a 746-bed non-profit, acute care teaching hospital located in Phoenix, Arizona, providing tertiary care and healthcare services to the Arizona region and surrounding states. [1]
The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
The Mayo Clinic Cancer Center is one of the oldest NCI-designated cancer centers in the United States, having first been designated in 1973. [3] The main location of the Mayo Clinic is in Rochester, MN. Campuses in Arizona and Florida opened later and became part of the Mayo Clinic Cancer Center in 2003. [4] [5]
Cal Yee Farms' recall of some of its products last month has been increased to the highest risk level by the U.S. Food and Drug Administration (FDA) for three of its chocolate offerings. On Dec ...