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In October 2024, the Committee for Veterinary Medicinal Products of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization for the veterinary medicinal product Duotic, Ear gel, intended for dogs. [3] The applicant for this veterinary medicinal product is Dechra Regulatory B.V. [3]
prednisolone – glucocorticoid (steroid) used in the management of inflammation and auto-immune disease, primarily in cats; prednisone – glucocorticoid (steroid) used in the management of inflammation and auto immune disease; pregabalin – neuropathic pain reliever and anti-convulsant; propofol – short acting intravenous drug used to ...
Marbofloxacin can be used both orally and topically. It is particularly used for infections of the skin, respiratory system and mammary glands in dogs and cats, as well as with urinary tract infections. For dogs, a dose ranges from 2.75 - 5.5 mg/kg once a day.
It is used as ear drops. [ 1 ] Ciprofloxacin, a fluoroquinolone antibiotic , has shown in vitro activity against many Gram-positive and Gram-negative bacteria including Staphylococcus aureus , Streptococcus pneumoniae , Haemophilus influenzae , Moraxella catarrhalis , and Pseudomonas aeruginosa .
Drug induced hypoadrenocorticism is caused during abrupt cessation of a steroid medication. [ 16 ] [ 19 ] During steroid treatment, the adrenal glands do not function fully. The body senses the levels of the exogenous steroids in the system and therefore does not signal for additional production. [ 13 ]
Kenacomb ear drops, containing triamcinolone acetonide, neomycin and gramicidin (antibiotics) and nystatin [21] Sofradex ear drops containing neomycin and gramicidin (antibiotics) plus dexamethasone (a steroid) [22] Antibiotics for ear infections are prescribed for infections that are recurrent or difficult for the body to clear.
In dogs, Bimasone is approved for use for musculoskeletal conditions due to inflammation of muscles or joints, such as arthritis, osteoarthritis, intervertebral disc disease, and myositis. [3] The drug has proven useful in treating canine ear infections (otitis externa) when used with topical medication for similar reasons. [ 3 ]
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent.