Search results
Results From The WOW.Com Content Network
The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).
It contains the growth plate, the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses. The metaphysis contains a diverse population of cells including mesenchymal stem cells , which give rise to bone and fat cells, as well as hematopoietic stem cells which give rise to a variety of ...
In long bones, the secondary centers appear in the epiphyses. [2] At the end of the formation of the secondary ossification center, the only two areas where the cartilage remains is at the articular cartilage covering the epiphysis and at the epiphyseal plate between the epiphysis and diaphysis. [3] A schematic for long bone endochondral ...
However, these transverse notches lack the typical cell columns found in normal growth plates, and do not contribute significantly to longitudinal bone growth. [12] Pseudo-epiphyses are found at the distal end of the first metacarpal bone in 80% of the normal population, and at the proximal end of the second metacarpal in 60%. [11]
Epiphyseal growth plate: This transverse layer lies between the epiphysis and diaphysis. It’s composed of highly active chondrocytes and responsible for longitudinal bone growth. Consequently, the bone elongates at this growth plate until closure occurs at skeletal maturity.
During growth, the growth plates are located distally on the metatarsals, except on the first metatarsal where it is located proximally. Yet it is quite common to have an accessory growth plate on the distal first metatarsal. [5]
The longitudinal growth of long bones is a result of endochondral ossification at the epiphyseal plate. Bone growth in length is stimulated by the production of growth hormone (GH), a secretion of the anterior lobe of the pituitary gland .
The canal of the nutrient foramen is directed away from more active end of bone when one end grows more than the other. When bone grows at same rate at both ends, the nutrient artery is perpendicular to the bone. Most other bones (e.g. vertebrae) also have primary ossification centers, and bone is laid down in a similar manner. Secondary centers