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In neuroscience, the default mode network (DMN), also known as the default network, default state network, or anatomically the medial frontoparietal network (M-FPN), is a large-scale brain network primarily composed of the dorsal medial prefrontal cortex, posterior cingulate cortex, precuneus and angular gyrus.
However, children show greater medial prefrontal cortex activation than adults when performing self-knowledge retrieval tasks. Additionally, children and adults activate different specific regions in the medial prefrontal cortex. Adults activate the posterior precuneus more while children activate the anterior precuneus and the posterior ...
The prefrontal cortex has been defined based on cytoarchitectonics by the presence of a cortical granular layer IV.It is not entirely clear who first used this criterion. Many of the early cytoarchitectonic researchers restricted the use of the term prefrontal to a much smaller region of cortex including the gyrus rectus and the gyrus rostralis (Campbell, 1905; G. E. Smith, 1907; Brodmann ...
Many other researchers have used this task, including Guitton et al. and Pierrot-Deseilligny et al. In a well-known study by Guitton et al. (1985), patients with epilepsy who had undergone therapeutic removal of their dorsolateral prefrontal cortex were administered the anti-saccade task. Their performance was compared to healthy controls and ...
The locus coeruleus is activated by stress, and will respond by increasing norepinephrine secretion, which in turn will alter cognitive function (through the prefrontal cortex), increase motivation (through nucleus accumbens), activate the hypothalamic-pituitary-adrenal axis, and increase the sympathetic discharge/inhibit parasympathetic tone ...
The prefrontal cortex, being a central hub for executive functions, relies on the input from the mesocortical pathway to modulate and fine-tune cognitive processes essential for goal-directed behavior and decision-making. [20] Dysregulation of the neurons in this pathway has been connected to ADHD. [16]
The mesocortical pathway is a dopaminergic pathway that connects the ventral tegmentum to the prefrontal cortex. It is one of the four major dopamine pathways in the brain . It is essential to the normal cognitive function of the dorsolateral prefrontal cortex (part of the frontal lobe), and is thought to be involved in cognitive control ...
The prefrontal cortex accommodates many systems and tasks working independently, dependently, and interacting with the SAS. The SAS functioning depends on multiple specific systems, and structures in the brain. [12] Throughout the 1980s and 1990s, much neuropsychological research was conducted on the frontal lobes and prefrontal cortex (PFC). [9]