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Post-traumatic epilepsy (PTE) is a form of acquired epilepsy that results from brain damage caused by physical trauma to the brain (traumatic brain injury, abbreviated TBI). [1] A person with PTE experiences repeated post-traumatic seizures (PTS, seizures that result from TBI) more than a week after the initial injury. [ 2 ]
Some types of seizures may change brain structure, while others appear to have little effect. [103] Gliosis, neuronal loss, and atrophy of specific areas of the brain are linked to epilepsy but it is unclear if epilepsy causes these changes or if these changes result in epilepsy. [103]
PTS occur in about 3.1% of traumatic brain injuries, but the severity of injury affects the likelihood of occurrence. [9] The most important factor in whether a person will develop early and late seizures is the extent of the damage to the brain. [2] More severe brain injury also confers a risk for developing PTS for a longer time after the ...
First line therapy for epilepsy involves treatment with anticonvulsive drugs, also called antiepileptic drugs– most patients will respond to trials of one or two different medications. [5] The goal of treatment is the elimination of seizures, since uncontrolled seizures carry significant risks, including injury and sudden unexpected death in ...
Epileptogenesis is the gradual process by which a typical brain develops epilepsy. [1] Epilepsy is a chronic condition in which seizures occur. [2] These changes to the brain occasionally cause neurons to fire in an abnormal, hypersynchronous manner, known as a seizure. [3]
The brain damage caused by radiation depends on where the brain tumor is located, the amount of radiation used, and the duration of the treatment. Radiosurgery can also lead to tissue damage that results in about 1 in 20 patients requiring a second operation to remove the damaged tissue.
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