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The transtheoretical model (TTM) can be used to determine when treatment can begin and which method will be most effective. If treatment begins too early, it can cause a person to become defensive and resistant to change. [17] [18] The rate of successful lifetime recovery is around 50%, a metastudy on 415 reports (1868-2011) showed. [19]
A third option is to defer treatment until symptoms occur. This method should not be used in patients with prior, alcohol-related seizures. This has been effective in randomized controlled trials. [7] [8] A non-randomized, before and after, observational study found that symptom-triggered therapy was advantageous. [9]
Medical treatment for alcohol detoxification usually involves administration of a benzodiazepine, in order to ameliorate alcohol withdrawal syndrome's adverse impact. [139] [140] The addition of phenobarbital improves outcomes if benzodiazepine administration lacks the usual efficacy, and phenobarbital alone might be an effective treatment. [141]
Treatment can be a long process and the duration is dependent upon the patient's needs and history of substance use. Research has shown that most patients need at least three months of treatment and longer durations are associated with better outcomes. [3] Prescription drug addiction does not discriminate.
The addiction involves genetic predisposition, corrupted brain chemistry, entrenched environmental factors and any number of potential mental-health disorders — it requires urgent medical intervention. According to the medical establishment, medication coupled with counseling is the most effective form of treatment for opioid addiction.
Drug detoxification (informally, detox) is variously construed or interpreted as a type of "medical" intervention or technique in regards to a physical dependence mediated by a drug; as well as the process and experience of a withdrawal syndrome or any of the treatments for acute drug overdose (toxidrome).
Nearly 30% of patients in the US trial did not complete induction. [33] In real-world settings, a review of more than 40,000 patient records found that while methadone and buprenorphine reduced risk of fatal overdose, naltrexone administration showed no greater effect on overdose or subsequent emergency care than counseling alone. [30]
The Sinclair Method, as the protocol has been named, was the subject of a large body of laboratory studies [7] and used in over 90 clinical trials around the world. [8] [9] The Sinclair Method, which is simply taking an opioid antagonist before drinking, has been found to be successful in about 80% of Alcohol Use Disorder (AUD) sufferers.
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