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Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats.
These mites live within the fur of cats and dogs, feeding on sloughed scales of skin. Often this causes little reaction in the host, but pruritus, seborrhea and pustules in the skin may develop as an allergic reaction to the mites. The adult mites are visible crawling in the fur and may cause similar skin reactions in the pet's owner.
Potency of fluralaner is comparable to fipronil ... as a topical treatment for cats in November 2019. ... For treating mites in chickens, ...
A single treatment with a topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel was shown to be efficient for the prevention of Otodectes cynotis infestation in cats. Methoprene is able to prevent eggs from hatching and stop mites from maturing; the rest are all parasite-killing drugs.
Chemical structure of fipronil, a common phenylpyrazole insecticide. Phenylpyrazole insecticides are a class of chemically-related broad-spectrum insecticides. [1] The chemical structures of these insecticides are characterized by a central pyrazole ring with a phenyl group attached to one of the nitrogen atoms of the pyrazole.