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Self-healing hydrogels are a specialized type of polymer hydrogel.A hydrogel is a macromolecular polymer gel constructed of a network of crosslinked polymer chains. Hydrogels are synthesized from hydrophilic monomers by either chain or step growth, along with a functional crosslinker to promote network formation.
Hydrogels based on non-covalent interactions or dynamic covalent chemistry can exhibit self-healing properties after cutting or breaking. [137] Hydrogels that can fully fluidize followed by self-healing are of particular interest in biomedical engineering for the development of injectable hydrogels for tissue regeneration or 3D bioprinting inks.
Although many studies have demonstrated the irreversible compression of hydrogels induced under ultrasound, Goncalves et al. designed hydrogel-based nanoparticles that were capable of “self-healing”, meaning they were able to return to their original form following drug release from its depot. [28]
Self-healing hydrogels automatically and reversibly repair damage done due to mechanical and chemical stress. [25] Self-healing mechanisms can involve "dynamic covalent bonding, non-covalent interactions", and mixed interactions. [25] Covalent interactions involved in self-healing include Schiff base formation and disulfide exchange. [25]
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[77] [78] [79] Hydrogels with reversible chemistry are required to allow for fluidization during injection/printing followed by self-healing of the original hydrogel structure. [80] Investigate cell biomechanical functions combined with holotomography microscopy; Provide absorption, desloughing and debriding of necrotic and fibrotic tissue
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Elton John's gift may be his song, but that doesn't mean he loves them all.. During an appearance on The Late Show with Stephen Colbert on Tuesday, Dec. 17, the 77-year-old musician spoke about ...