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While NAC has been demonstrated to modulate glutamate neurotransmission in adult humans who are addicted to cocaine, NAC does not appear to modulate glutamate neurotransmission in healthy adult humans. [84] NAC has been hypothesized to exert beneficial effects through its modulation of glutamate and dopamine neurotransmission as well as its ...
Early symptoms include headache, dizziness, fast heart rate, shortness of breath, and vomiting. [2] This phase may then be followed by seizures, slow heart rate, low blood pressure, loss of consciousness, and cardiac arrest. [2] Onset of symptoms usually occurs within a few minutes. [2] [3] Some survivors have long-term neurological problems. [2]
The output neurons of the nucleus accumbens send axonal projections to the basal ganglia and the ventral analog of the globus pallidus, known as the ventral pallidum (VP). ). The VP, in turn, projects to the medial dorsal nucleus of the dorsal thalamus, which projects to the prefrontal cortex as well as back to the ventral and to dorsal stri
Arsenic poisoning (or arsenicosis) is a medical condition that occurs due to elevated levels of arsenic in the body. [4] If arsenic poisoning occurs over a brief period of time, symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood. [1]
Mouth and genital ulcers with inflamed cartilage syndrome or MAGIC syndrome is a condition in which an individual exhibits symptoms of both relapsing polychondritis (RP) and Behcet's disease (BD). [1] Inflammatory ulcers in the mouth, genitalia, and skin are the hallmark of Behcet's disease (BD), a multisystem illness that is chronic and ...
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Saliva is an important component of the taste mechanism. Saliva both interacts with and protects the taste receptors in the mouth. [5] Saliva mediates sour and sweet tastes through bicarbonate ions and glutamate, respectively. [6] The salt taste is induced when sodium chloride levels surpass the concentration in the saliva. [6]
Acute atrophic candidiasis may feel like the mouth has been scalded with a hot liquid. [5] Another potential symptom is a metallic, acidic, salty or bitter taste in the mouth. [5] [8] The pseudomembranous type rarely causes any symptoms apart from possibly some discomfort or bad taste due to the presence of the membranes.