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Vitamin D is essential for bone health and immune function, and deficiency is common. Consoider one of these vitamin D supplements if you're not getting enough.
$20.99 at Amazon. Orange Vitamin D3. Rated at 4.7 stars by over 6,000 happy customers on Amazon, this daily vitamin is a tried-and-true product that's affordable and even offers a refreshing ...
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
For example, CYP11A1, an enzyme chiefly known for its role in steroidogenesis, has been found to hydroxylate vitamin D3 at several positions, including C-20, C-22, and C-23, without cleaving the side chain. The resulting metabolites, such as 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3, act as inverse agonists for RORα and RORγ2.
Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3] These two forms of vitamin D are metabolized in the liver and stored as 25-hydroxyvitamin D. [ 4 ] Before biological use, the storage form must be converted into an active form.
Calcifediol supplements have been used in some studies to improve vitamin D status. [4] Indications for their use include vitamin D deficiency or insufficiency, refractory rickets ( vitamin D resistant rickets ), familial hypophosphatemia , hypoparathyroidism , hypocalcemia and renal osteodystrophy and, with calcium, in primary or ...
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