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Postinflammatory hyperpigmentation (PIH) is a skin condition characterized by the darkening of the skin (hyperpigmentation) following an inflammatory injury, such as acne, dermatitis, infectious disease, or trauma. Less frequently, it may occur as a complication of a medical procedure performed on the skin. It is a common cause of skin ...
Some reactions, such as pain, may appear immediately. Others may be delayed, such as erythema which may appear 24–96 hours after injection. [2] ISRs commonly seen with subcutaneous injections include: Bleeding and bruising [3] Erythema (redness) Pain; Pruritis (itching) [4] Swelling [5] Induration (hardening of the skin) [6] Discoloration [6]
Postinflammatory hypopigmentation is a common consequence of cutaneous inflammatory disorders. Certain conditions, like lichen striatus (LS) and pityriasis lichenoides chronica (PLC), typically cause postinflammatory hypopigmentation as opposed to hyperpigmentation .
Erythema (Ancient Greek: ἐρύθημα, from Greek erythros 'red') is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. [1] It occurs with any skin injury, infection, or inflammation .
Image at right shows influx of inflammatory cells including eosinophils and neutrophils in the dermis (solid arrow) and blister cavity (dashed arrows), and deposition of fibrin (asterisks). [15] However, the diagnosis of bullous pemphigoid consist of at least 2 positive results out of 3 criteria: [ 19 ]
The redness starts to fade and it gradually becomes softer and smaller until it disappears. Each nodule usually heals completely without scarring over the course of about two weeks. [3] [4] Joint pain and inflammation sometimes continue for several weeks or months after the nodules appear. [5] Less common variants of erythema nodosum include:
Smooth red-topped small papules which merge into plaques, small fluid-filled blisters (papulovesicles) [2] and less commonly target-shaped lesions which look like erythema multiforme may be visible. [5] In addition, it may occur in other parts of the body in some people treated for inflammatory skin diseases with phototherapy. [2]
Although there are a multitude of varying appearances, the id reaction often presents with symmetrical red patches of eczema with papules and vesicles, particularly on the outer sides of the arms, face and trunk which occur suddenly and are intensely itchy occur a few days to a week after the initial allergic or irritant dermatitis.