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  2. Chondroitin sulfate - Wikipedia

    en.wikipedia.org/wiki/Chondroitin_sulfate

    Chondroitin sulfate is a sulfated glycosaminoglycan (GAG) [1] composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan. [1] A chondroitin chain can have over 100 individual sugars, each of which can be sulfated in variable positions and quantities ...

  3. Glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Glycosaminoglycan

    Glycosaminoglycan. The repeating disaccharide unit (GlcUA (1β→3)GalNAc (1β→4)) n of chondroitin sulfate. For polysaccharide nomenclature see here. R 1, R 2, R 3 may have different values. Glycosaminoglycans[1] (GAGs) or mucopolysaccharides[2] are long, linear polysaccharides consisting of repeating disaccharide units (i.e. two-sugar units).

  4. Chondroitin - Wikipedia

    en.wikipedia.org/wiki/Chondroitin

    A chondroitin is a chondrin derivative. [1] Types include: Chondroitin sulfate. Dermatan sulfate. Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. [2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in ...

  5. Chondroitin sulfate proteoglycan - Wikipedia

    en.wikipedia.org/wiki/Chondroitin_sulfate...

    Chondroitin sulfate proteoglycan. Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural components of a variety of human tissues, including cartilage, and also play key roles in neural development and glial scar formation.

  6. Clinical trials on glucosamine and chondroitin - Wikipedia

    en.wikipedia.org/wiki/Clinical_trials_on_glucos...

    The authors of the study analyzed the moderate-to-severe pain group and found that in this group, the combination of glucosamine and chondroitin was more effective at providing pain relief than the positive control with 79% of the glucosamine group reporting at least a 20% reduction in pain compared to 70% for celecoxib and only 54% reporting a ...

  7. Proteoglycan - Wikipedia

    en.wikipedia.org/wiki/Proteoglycan

    Proteoglycans are proteins [1] that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein " with one or more covalently attached glycosaminoglycan (GAG) chain (s). [2] The point of attachment is a serine (Ser) residue to which the glycosaminoglycan is joined through a tetrasaccharide bridge (e.g. chondroitin sulfate ...