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A 2023 review concluded that vaping causes significant, potentially harmful effects on many cardiovascular parameters. [159] A 2024 review attributed cardiovascular effects to oxidative stress, inflammation, endothelial dysfunction, atherosclerosis, hemodynamic effects, and platelet function. [160]
Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
Based on reports from several states, patients have experienced respiratory symptoms (cough, shortness of breath, or chest pain), while some have also experienced gastrointestinal symptoms (nausea, vomiting, or diarrhea) or non-specific symptoms (fatigue, fever, or weight loss). [2] Some cases reported mild to moderate gastrointestinal illness ...
U.S. health officials are investigating reports of 380 confirmed and probable cases of serious lung illnesses and at least six deaths linked to use of electronic cigarettes or vaping devices in 36 ...
Nor do doctors know where they had purchased the devices or e-liquids. Some patients said they'd used e-cigarette devices to inhale both nicotine and THC, the psychoactive ingredient in marijuana.
Lungs-Breathing in ultra-fine vapor particles can cause asthma attacks, wheezing, coughing and shortness of breath. Also, flavor chemicals such as diacetyl can permanently injure lungs.
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...